OC Register: Despite homers from Mike Trout, Shohei Ohtani and two from Justin Upton, Angels blow lead against Mariners

[AngelsWin.com]

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  Los Angeles Angels’ Kaleb Cowart misses a ground ball hit by Seattle Mariners’ Kristopher Negron as Mariners’ Ryon Healy, background right, runs to third base during the sixth inning of a baseball game, Saturday, Sept. 15, 2018, in Anaheim, Calif. Healy scored on the play. (AP Photo/Jae C. Hong)

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  Seattle Mariners’ Nelson Cruz watches during the first inning of a baseball game against the Los Angeles Angels, Saturday, Sept. 15, 2018, in Anaheim, Calif. (AP Photo/Jae C. Hong)

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  Seattle Mariners’ Robinson Cano walks off the field after striking out during the first inning of a baseball game against the Los Angeles Angels, Saturday, Sept. 15, 2018, in Anaheim, Calif. (AP Photo/Jae C. Hong)

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  Seattle Mariners starting pitcher Erasmo Ramirez throws against the Los Angeles Angels during the first inning of a baseball game, Saturday, Sept. 15, 2018, in Anaheim, Calif. (AP Photo/Jae C. Hong)

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  Los Angeles Angels’ Kole Calhoun dives to catch a ball hit by Seattle Mariners’ Dee Gordon during the eighth inning of a baseball game, Saturday, Sept. 15, 2018, in Anaheim, Calif. (AP Photo/Jae C. Hong)

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  Los Angeles Angels’ Mike Trout, right, slides into home plate as Seattle Mariners catcher Mike Zunino prepares to tag him during the sixth inning of a baseball game, Saturday, Sept. 15, 2018, in Anaheim, Calif. (AP Photo/Jae C. Hong)

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  Los Angeles Angels’ Shohei Ohtani, right, of Japan, stands next to Mike Trout before a baseball game against the Seattle Mariners, Saturday, Sept. 15, 2018, in Anaheim, Calif. (AP Photo/Jae C. Hong)

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  Los Angeles Angels’ Shohei Ohtani, of Japan, is congratulated by third base coach Dino Ebel after hitting a home run during the first inning of a baseball game against the Seattle Mariners, Saturday, Sept. 15, 2018, in Anaheim, Calif. (AP Photo/Jae C. Hong)

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  Los Angeles Angels’ Mike Trout, left, is tagged out by Seattle Mariners catcher Mike Zunino as he tries to score on a single hit by Shohei Ohtani during the sixth inning of a baseball game, Saturday, Sept. 15, 2018, in Anaheim, Calif. (AP Photo/Jae C. Hong)

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  Los Angeles Angels’ Mike Trout, right, slides into home plate as Seattle Mariners catcher Mike Zunino prepares to tag him during the sixth inning of a baseball game, Saturday, Sept. 15, 2018, in Anaheim, Calif. (AP Photo/Jae C. Hong)

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  Los Angeles Angels’ Shohei Ohtani, of Japan, slides back to first base during the sixth inning of a baseball game against the Seattle Mariners, Saturday, Sept. 15, 2018, in Anaheim, Calif. (AP Photo/Jae C. Hong)

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ANAHEIM — A night that began with an Angels milestone ended as another disappointing loss.

Mike Trout and Shohei Ohtani, the Angels’ two brightest stars, hit back-to-back homers for the first time on Saturday night, and Justin Upton added two, but the Angels couldn’t hold an early four-run lead and they lost 6-5 to the Seattle Mariners.

Robinson Canó’s three-run double against Williams Jerez put the Mariners on top in the eighth.

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In the first inning, Trout blasted his 34th homer of the year, a two-run shot. Ohtani then followed with a drive to straightaway center, his 20th.

Once again connecting himself to Babe Ruth, Ohtani became the first player since Ruth to hit 20 homers in a season in which he’d won multiple games as a pitcher.

Ruth did it in 1919 and 1921, and no one else had done it in major league history.

The Angels padded the lead to 4-0 on Justin Upton’s 28th homer of the season. It was Upton’s second homer in three games, after not hitting one for nearly a month. He would hit another homer in the ninth, after the Angels fell behind 6-4.

It was too little to overcome the deficit created by a shaky night from the bullpen.

Andrew Heaney gave up a pair of solo homers in the fifth and left the bullpen to work four innings, handing them a 4-2 lead.

Justin Anderson gave up a run in the sixth. After Ty Buttrey’s scoreless seventh, José Álvarez entered in the eighth. He struck out Kristopher Negron, but the ball got away from catcher José Briceño and Negron took first. Álvarez then walked Guillermo Heredia.

Jim Johnson got an out and walked a batter to load the bases.

Jerez, who had allowed at least one run in his previous five games, then came in to face Canó. He blasted a drive off the center field fence, clearing the bases.

More to come on this story.

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